Putatively Noncoding Transcripts Show Extensive Association with Ribosomes
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Putatively Noncoding Transcripts Show Extensive Association with Ribosomes
There have been recent surprising reports that whole genes can evolve de novo from noncoding sequences. This would be extraordinary if the noncoding sequences were random with respect to amino acid identity. However, if the noncoding sequences were previously translated at low rates, with the most strongly deleterious cryptic polypeptides purged by selection, then de novo gene origination would...
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ژورنال
عنوان ژورنال: Genome Biology and Evolution
سال: 2011
ISSN: 1759-6653
DOI: 10.1093/gbe/evr099